A facile and economic electrochemical sensor for methylmalonic acid: a potential biomarker for vitamin B12 deficiency
Rijo Rajeev, Libina Benny, Moulisha Roy, Agnus T. Mathew, K. B. Akshaya, Anitha Varghese, Gurumurthy Hegde
Abstract
A facile and cost-effective method based on a modified pencil graphite electrode (PGE) has been developed for sensing of methylmalonic acid (MMA). The fabricated sensor showed a linear dynamic range (0.50 pM–55 nM) and a LOD of (0.16 pM).
Topics & Concepts
ChemistryVitamin B12Methylmalonic acidElectrochemistryElectrochemical gas sensorLinear rangeElectrodeBiomarkerGraphitePencil (optics)ChromatographyBiochemistryDetection limitOrganic chemistryPhysical chemistryEngineeringMechanical engineeringElectrochemical sensors and biosensorsElectrochemical Analysis and ApplicationsConducting polymers and applications