Blood DNA methylation sites predict death risk in a longitudinal study of 12, 300 individuals
Elena Colicino, Riccardo E. Marioni, Cavin Ward‐Caviness, Rahul Gondalia, Weihua Guan, Brian Chen, Pei-Chien Tsai, Tianxiao Huan, Xu Gao, Golareh Agha, Joel Schwartz, Pantel Vokonas, Allan C. Just, John M. Starr, Allan F. McRae, Naomi R. Wray, Peter M. Visscher, Jan Bressler, Wen Zhang, Toshiko Tanaka, Ann Zenobia Moore, Luke C. Pilling, Guosheng Zhang, James D. Stewart, Yun Li, Lifang Hou, Juan Castillo‐Fernandez, Tim D. Spector, Douglas P. Kiel, Joanne M. Murabito, Chunyu Liu, Mike Mendelson, Tim Assimes, Devin Absher, Phil S. Tsaho, Ake T. Lu, Luigi Ferrucci, Rory Wilson, Mélanie Waldenberger, Holger Prokisch, Stefania Bandinelli, Jordana T. Bell, Daniel Levy, Ian J. Deary, Steve Horvath, Jim Pankow, Annette Peters, Eric A. Whitsel, Andrea Baccarelli
Abstract
) linked to immune responses and cardiometabolic diseases. These sites may serve as useful clinical tools for mortality risk assessment and preventative care.