A synthetic biology roadmap for sustainable production of the plant-originated anti-cancer drug paclitaxel
Chun-Lin Tan, Xin Yu, Hui-Cheng Feng, Jonathan Gershenzon, Y Liu, Sheng-Hong Li
Topics & Concepts
Synthetic biologyComputational biologyBiologyPaclitaxelDrug discoveryMetabolic engineeringSystems biologyBiotechnologySustainable productionDrug developmentBiochemical engineeringKey (lock)BioproductionChemical biologyBiosynthesisCyanobacteriaDrugGenome editingMetabolic pathwaySustainabilityHeterologousNatural productComputer scienceGenomicsChassisProduction (economics)ResveratrolCRISPRCancer Treatment and PharmacologyMicrobial Natural Products and BiosynthesisMicrobial Metabolism and Applications