Peripheral CD8+ T cell characteristics associated with durable responses to immune checkpoint blockade in patients with metastatic melanoma
Benjamin P. Fairfax, Chelsea Taylor, Robert Watson, Isar Nassiri, Sara Danielli, Hai Fang, Elise A. Mahé, Rosalin Cooper, Victoria K. Woodcock, Zoë Traill, Hussein Al‐Mossawi, Julian C. Knight, Paul Klenerman, Miranda Payne, Mark R. Middleton
Topics & Concepts
CD8Immune checkpointCytotoxic T cellT cellImmune systemBiologyNivolumabBlockadeImmunologyTranscriptomeMelanomaCancer researchImmunotherapyMedicineGeneGene expressionReceptorGeneticsIn vitroCAR-T cell therapy researchCancer Immunotherapy and BiomarkersImmune Cell Function and Interaction