Comparison of the Quantitative DiaSorin Liaison Antigen Test to Reverse Transcription-PCR for the Diagnosis of COVID-19 in Symptomatic and Asymptomatic Outpatients
Stefanie Lefever, Christophe Indevuyst, Lize Cuypers, Klaas Dewaele, Nicolas Yin, Frédéric Cotton, Elizaveta Padalko, Matthijs Oyaert, Julie Descy, Etienne Cavalier, Marc Van Ranst, Emmanuel André, Katrien Lagrou, Pieter Vermeersch
Abstract
We evaluated the quantitative DiaSorin Liaison severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antigen test in symptomatic and asymptomatic individuals consulting their general practitioners (GPs) during a period of stable intense virus circulation (213/100,000 habitants per day). Leftover reverse transcription-PCR (RT-PCR) positive ( n = 204) and negative ( n = 210) nasopharyngeal samples were randomly selected among fresh routine samples collected from patients consulting their GPs.
Topics & Concepts
AsymptomaticMedicineConfidence intervalViral loadInternal medicineAntigenCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)GastroenterologyVirusVirologyImmunologyDiseaseInfectious disease (medical specialty)SARS-CoV-2 detection and testingSARS-CoV-2 and COVID-19 ResearchRespiratory viral infections research