NRF2 Deficiency Promotes Ferroptosis of Astrocytes Mediated by Oxidative Stress in Alzheimer’s Disease
Zhi Tang, Zhuyi Chen, Min Guo, Yaqian Peng, Yan Xiao, Zhi-Zhong Guan, Ruiqing Ni, Xiaolan Qi
Topics & Concepts
Oxidative stressReactive oxygen speciesLipid peroxidationGPX4NADPH oxidaseAstrocyteChemistryCell biologyNeurotoxicityNOX4BiologyGlutathione peroxidaseBiochemistrySuperoxide dismutaseEndocrinologyCentral nervous systemOrganic chemistryToxicityFerroptosis and cancer prognosisGenomics, phytochemicals, and oxidative stressEpigenetics and DNA Methylation