Timosaponin BII improved osteoporosis caused by hyperglycemia through promoting autophagy of osteoblasts via suppressing the mTOR/NFκB signaling pathway
Nani Wang, Pingcui Xu, Renjie Wu, Xuping Wang, Yongjun Wang, Dan Shou, Yan Zhang
Topics & Concepts
AutophagyChemistryPI3K/AKT/mTOR pathwayApoptosisDownregulation and upregulationPharmacologyLY294002Cell biologyBiochemistryBiologyGeneBone Metabolism and DiseasesProtein Tyrosine PhosphatasesNF-κB Signaling Pathways