Litcius/Paper detail

Diastereo- and enantioselective 1,3-hydrofunctionalization of trisubstituted alkenes by a directing relay

Wei Zhao, En‐Ze Lin, Ke-Zhi Chen, Yu-Wen Sun, Bi‐Jie Li

2025Nature Chemistry9 citationsDOI

Topics & Concepts

AlkeneChemistryEnantiopure drugEnantioselective synthesisStereocenterCatalysisAllylic rearrangementCombinatorial chemistryStereochemistryTetrapeptideAmideRetrosynthetic analysisMethylenePhthalimideStereoselectivityStereoisomerismCleaveCatalytic cycleNucleophileChemoselectivityCatalytic C–H Functionalization MethodsAsymmetric Synthesis and CatalysisAsymmetric Hydrogenation and Catalysis