Anticancer effect evaluation in vitro and in vivo of iridium(III) polypyridyl complexes targeting DNA and mitochondria
Huiwen Zhang, Tian Li, Rongxing Xiao, Yi Zhou, Yuanyuan Zhang, Jing Hao, Yunjun Liu, Juping Wang
Topics & Concepts
ChemistryApoptosisIn vivoCytotoxicityFlow cytometryIntracellularReactive oxygen speciesMolecular biologyIn vitroBiochemistryBiologyBiotechnologyMetal complexes synthesis and propertiesCancer therapeutics and mechanismsSynthesis and biological activity