Research progress on classical traditional Chinese medicine Taohong Siwu decoction in the treatment of coronary heart disease
XueZhen Wang, Tong Wang, YingZheng Wang, Xiao Li, Qian Chen, Yuan Wang, Xiaoyu Zhang, Huaxin Wang, Haijun Zhao, Yue Mou, L. Xia, Yanan Zhang
Abstract
The pathogenesis of coronary heart disease is closely related to blood stasis. Taohong Siwu decoction (THSW for short) is one of the most widely used prescriptions for activating blood and removing stasis. Clinical research has confirmed its curative effect on coronary heart disease. However, its underlying mechanism remains unclear. Therefore, this paper reviewed the clinical efficacy of THSW and determine its effective components based on a comprehensive literature review. Furthermore, the core components and targets of THSW in treating coronary heart disease using molecular docking were verified, and the interaction sites were predicted to construct a theoretical basis for the clinical application of THSW.