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TOPK mediates hypoxia-induced epithelial-mesenchymal transition and the invasion of nonsmall-cell lung cancer cells via the HIF-1α/snail axis

Jung‐Hwan Park, Minho Moon, Jong-Seok Kim, Sang‐Muk Oh

2020Biochemical and Biophysical Research Communications18 citationsDOI

Topics & Concepts

Gene knockdownSnailEpithelial–mesenchymal transitionHypoxia (environmental)Cancer researchBiologyCellTranscription factorSignal transductionLung cancerHypoxia-inducible factorsCancer cellMetastasisCancerCell biologyInternal medicineMedicineCell cultureChemistryGeneBiochemistryEcologyOxygenOrganic chemistryGeneticsFOXO transcription factor regulationCancer, Hypoxia, and MetabolismATP Synthase and ATPases Research
TOPK mediates hypoxia-induced epithelial-mesenchymal transition and the invasion of nonsmall-cell lung cancer cells via the HIF-1α/snail axis | Litcius