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Cystine supplementation rebalances the redox homeostasis of microenvironment in non-small cell lung cancer cells and reverses their resistance to docetaxel

Sijia Li, Bei Cao, Zhenyao Lu, Runbin Sun, Suhan Guo, Yuan Xie, Jiye Aa, Guangji Wang

2021Acta Pharmacologica Sinica16 citationsDOIOpen Access PDF

Topics & Concepts

GlutathioneA549 cellCystineCancer cellChemistryCell biologyGlutathione disulfideOxidative stressHomeostasisReactive oxygen speciesBiochemistryBiologyCellCancerCysteineEnzymeGeneticsCancer, Hypoxia, and MetabolismMetabolomics and Mass Spectrometry StudiesCancer, Lipids, and Metabolism
Cystine supplementation rebalances the redox homeostasis of microenvironment in non-small cell lung cancer cells and reverses their resistance to docetaxel | Litcius