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Understanding the Unique Microenvironment in the Aging Liver

Yalei Zhao, Ya Yang, Qian Li, ­Jun Li­

2022Frontiers in Medicine26 citationsDOIOpen Access PDF

Abstract

In the past decades, many studies have focused on aging because of our pursuit of longevity. With lifespans extended, the regenerative capacity of the liver gradually declines due to the existence of aging. This is partially due to the unique microenvironment in the aged liver, which affects a series of physiological processes. In this review, we summarize the related researches in the last decade and try to highlight the aging-related alterations in the aged liver.

Topics & Concepts

LongevityBiologySuccessful agingNeuroscienceMedicineGerontologyPancreatic function and diabetesLiver physiology and pathologyGenetics, Aging, and Longevity in Model Organisms
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