A direct high-throughput protein quantification strategy facilitates discovery and characterization of a celastrol-derived BRD4 degrader
N. Connor Payne, Semer Maksoud, Bakhos A. Tannous, Ralph Mazitschek
Topics & Concepts
CelastrolThroughputBRD4Characterization (materials science)Computer scienceComputational biologyChemistryBiologyNanotechnologyBromodomainMaterials scienceHistoneDNABiochemistryApoptosisTelecommunicationsWirelessProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysMultiple Myeloma Research and Treatments