Checkpoint-mediated DNA polymerase ε exonuclease activity curbing counteracts resection-driven fork collapse
Grazia Pellicanò, Mohammed Al Mamun, Dolores Jurado-Santiago, Sara Villa‐Hernández, Xingyu Yin, Michele Giannattasio, Michael C. Lanz, Marcus B. Smolka, Joseph T.P. Yeeles, Katsuhiko Shirahige, Miguel García–Díaz, Rodrigo Bermejo
Topics & Concepts
BiologyDNA replicationDNA polymeraseExonucleaseCell biologyDNA polymerase IIPolymeraseG2-M DNA damage checkpointMolecular biologyDNACell cycle checkpointGeneticsGeneCell cycleReverse transcriptaseRNADNA Repair MechanismsGenomics and Chromatin DynamicsCRISPR and Genetic Engineering