LBA-4 Results from an expanded phase 1 trial of botensilimab (BOT), a multifunctional anti-CTLA-4, plus balstilimab (BAL; anti-PD-1) for metastatic heavily pretreated microsatellite stable colorectal cancer (MSS CRC)
Andrea J. Bullock, Marwan Fakih, Michael S. Gordon, Apostolia M. Tsimberidou, Anthony B. El-Khoueiry, Breelyn A. Wilky, A. Pimentel, Kim Margolin, Daruka Mahadevan, Ani Sarkis Balmanoukian, Rachel E. Sanborn, Gary K. Schwartz, Ghassan K. Abou‐Alfa, Bruno Bockorny, Justin C. Moser, Sunil Sharma, Joseph E. Grossman, Katherine Rosenthal, Steven O’Day, Heinz‐Josef Lenz, Benjamin L. Schlechter
Topics & Concepts
MedicineInternal medicinePopulationColorectal cancerPhases of clinical researchResponse Evaluation Criteria in Solid TumorsGastroenterologyOncologyClinical endpointImmunotherapyAdverse effectCancerClinical trialSurgeryEnvironmental healthCancer Immunotherapy and BiomarkersColorectal Cancer Treatments and StudiesImmunotherapy and Immune Responses