CAPE and its synthetic derivative VP961 restore BACH1/NRF2 axis in Down Syndrome
Sara Pagnotta, Antonella Tramutola, Eugenio Barone, Fabio Di Domenico, Valeria Pittalà, Loredana Salerno, Valentina Folgiero, Matteo Caforio, Franco Locatelli, Stefania Petrini, D. Allan Butterfield, Marzia Perluigi
Topics & Concepts
KEAP1Caffeic acid phenethyl esterReactive oxygen speciesSuperoxide dismutaseOxidative stressChemistryTranscription factorBiochemistryNeuroprotectionCell biologyCatalaseAntioxidantBiologyGenePharmacologyCaffeic acidGenomics, phytochemicals, and oxidative stressAldose Reductase and TaurineCoenzyme Q10 studies and effects