Simultaneous determination of fluoxetine, venlafaxine, vortioxetine and their active metabolites in human plasma by LC–MS/MS using one-step sample preparation procedure
Martin Kertys, Michaela Krivosova, Igor Ondrejka, Igor Hrtánek, Ingrid Tonhajzerová, Juraj Mokrý
Topics & Concepts
ChemistryVenlafaxineHuman plasmaChromatographyVortioxetineSample preparationFluoxetineActive metaboliteMetaboliteMajor depressive disorderAntidepressantBiochemistryPsychologyNeuroscienceReceptorHippocampusSerotoninCognitionTreatment of Major DepressionTryptophan and brain disordersStress Responses and Cortisol