Attenuated polyethylene glycol immunogenicity and overcoming accelerated blood clearance of a fully PEGylated dendrimer
Chie Kojima, Junjie Yao, Kohei Nakajima, Motofumi Suzuki, Ayako Tsujimoto, Yuji Kuge, Mikako Ogawa, Akikazu Matsumoto
Topics & Concepts
PEGylationPolyethylene glycolPEG ratioBiodistributionDendrimerLiposomeImmunogenicityChemistryPharmacokineticsDrug deliveryPharmacologyDrug carrierMedicineImmunologyImmune systemBiochemistryIn vitroOrganic chemistryEconomicsFinanceRNA Interference and Gene DeliveryDendrimers and Hyperbranched PolymersNanoparticle-Based Drug Delivery