Wedelolactone alleviates cholestatic liver injury by regulating FXR-bile acid-NF-κB/NRF2 axis to reduce bile acid accumulation and its subsequent inflammation and oxidative stress
Meiqi Wang, Kai-Hui Zhang, Fangle Liu, Rui Zhou, Yun Zeng, Ali Chen, Yang Yu, Quan Xia, Chenchen Zhu, Chaozhan Lin
Topics & Concepts
Oxidative stressBile acidInflammationLiver injuryChemistryCholestasisNF-κBInternal medicineBiochemistryMedicineMedicinal Plants and NeuroprotectionDrug Transport and Resistance MechanismsDrug-Induced Hepatotoxicity and Protection