Human SLE variant NCF1-R90H promotes kidney damage and murine lupus through enhanced Tfh2 responses induced by defective efferocytosis of macrophages
Linyu Geng, Jian Zhao, Yun Deng, Ivan Molano, Xue Xu, Lingxiao Xu, Phillip Ruiz, Quan‐Zhen Li, Xuebing Feng, Miaojia Zhang, Wenfeng Tan, Diane L. Kamen, Sang‐Cheol Bae, Gary S. Gilkeson, Lingyun Sun, Betty P. Tsao
Topics & Concepts
Systemic lupus erythematosusMedicineImmunologyKidneyImmune systemInternal medicineEndocrinologyGerminal centerAutoantibodyEfferocytosisBiologyMacrophageAntibodyDiseaseB cellBiochemistryIn vitroNeutrophil, Myeloperoxidase and Oxidative Mechanismsinterferon and immune responsesPhagocytosis and Immune Regulation