Haploinsufficiency, Dominant Negative, and Gain-of-Function Mechanisms in Epilepsy: Matching Therapeutic Approach to the Pathophysiology
Gemma L. Carvill, Tyler Matheny, Jay R. Hesselberth, Scott Demarest
Topics & Concepts
HaploinsufficiencyEpilepsyMechanism (biology)NeurosciencePrecision medicineNeurologyBioinformaticsBiologyPhenotypeGeneMedicineGeneticsEpistemologyPhilosophyCRISPR and Genetic EngineeringGenetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research