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Anchoring β-CD on simvastatin-loaded rHDL for selective cholesterol crystals dissolution and enhanced anti-inflammatory effects in macrophage/foam cells

Jianhua He, Xiaoju Zhou, Fengfei Xu, Hongliang He, Shuangyan Ma, Xinyue Liu, Mengyuan Zhang, Wenli Zhang, Jianping Liu

2022European Journal of Pharmaceutics and Biopharmaceutics13 citationsDOI

Topics & Concepts

Foam cellSimvastatinEffluxChemistryCholesterolInflammationMacrophageBiophysicsDrug deliveryIntracellularCell biologyLipoproteinBiochemistryPharmacologyImmunologyBiologyIn vitroOrganic chemistryLipoproteins and Cardiovascular HealthCholesterol and Lipid MetabolismAtherosclerosis and Cardiovascular Diseases
Anchoring β-CD on simvastatin-loaded rHDL for selective cholesterol crystals dissolution and enhanced anti-inflammatory effects in macrophage/foam cells | Litcius