Calcium(II)-Mediated Three-Component Selenofunctionalization of Alkenes under Mild Conditions
Minyao Kuang, Haoran Li, Zhongyi Zeng, Hui Gao, Zhi Zhou, Xu‐Jia Hong, Wei Yi, Shengdong Wang
Abstract
A mild and general protocol involving amnio- and oxyselenation of diverse alkenes for the efficient synthesis of organo-Se compounds is achieved via an environmentally benign calcium-catalyzed three-component reaction. This selenofunctionalization reaction exhibits excellent substrate/functional group tolerance and high levels of chemo- and regioselectivity. Its utility was exemplified in the late-stage functionalization and even aggregation-induced emission luminogen labeling of organo-Se compounds.
Topics & Concepts
ChemistryRegioselectivitySubstrate (aquarium)Surface modificationFunctional groupCalciumCombinatorial chemistryCatalysisReaction conditionsOrganic chemistryPhysical chemistryOceanographyGeologyPolymerOrganoselenium and organotellurium chemistrySulfur-Based Synthesis TechniquesCatalytic C–H Functionalization Methods