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Ketamine-xylazine anesthesia depth affects auditory neuronal responses in the lateral superior olive complex of the gerbil

Zhizi Jing, Michael Pecka, Benedikt Grothe

2021Journal of Neurophysiology11 citationsDOIOpen Access PDF

Abstract

We studied how the depth of ketamine-xylazine anesthesia altered response properties of lateral superior olive complex neurons, and auditory brainstem evoked responses. Our results provide direct evidence that anesthesia depth affects auditory neuronal responses and reinforce the notion that both the anesthetics and the anesthesia depth should be considered when interpreting/comparing in vivo neuronal recordings.

Topics & Concepts

XylazineKetamineGerbilBrainstemNeuroscienceAnesthesiaPremovement neuronal activityMedicinePsychologyIschemiaCardiologyNeuroscience and Neuropharmacology ResearchNeural dynamics and brain functionOlfactory and Sensory Function Studies
Ketamine-xylazine anesthesia depth affects auditory neuronal responses in the lateral superior olive complex of the gerbil | Litcius