ZIGIR, a Granule-Specific Zn2+ Indicator, Reveals Human Islet α Cell Heterogeneity
Ebrahim H. Ghazvini Zadeh, ZhiJiang Huang, Jing Xia, Daliang Li, Howard W. Davidson, Wen-Hong Li
Abstract
-rich secretory granules and for engineering β cells with high insulin content for treating diabetes.
Topics & Concepts
Granule (geology)Enteroendocrine cellIsletCell sortingCell biologySomatostatinChemistryGlucagonCell typeCellBiologyBiophysicsInsulinBiochemistryEndocrine systemHormoneEndocrinologyPaleontologyPancreatic function and diabetesGenetics and Neurodevelopmental DisordersDiabetes Treatment and Management