mRNA vaccination induces tick resistance and prevents transmission of the Lyme disease agent
Andaleeb Sajid, Jaqueline Matias, Gunjan Arora, Cheyne Kurokawa, Kathleen DePonte, Xiao‐Tian Tang, Geoffrey E. Lynn, Ming-Jie Wu, Utpal Pal, Norma Olivares Strank, Norbert Pardi, Sukanya Narasimhan, Drew Weissman, Erol Fikrig
Abstract
attachment and the inability of the ticks to take a normal blood meal suggest that 19ISP may be used either alone or in conjunction with traditional pathogen-based vaccines for the prevention of Lyme disease, and potentially other tick-borne infections.
Topics & Concepts
Lyme diseaseVaccinationVirologyTickTransmission (telecommunications)LYMEBorrelia burgdorferiTick-borne diseaseMedicineBiologyImmunologyAntibodyComputer scienceTelecommunicationsVector-borne infectious diseasesVector-Borne Animal DiseasesViral Infections and Vectors