Transforming iodoquinol into broad spectrum anti-tumor leads: Repurposing to modulate redox homeostasis
I. CHAABAN, Haidy Hafez, Ibrahim AlZaim, Cynthia Tannous, Hanan M. Ragab, A. A. B. HAZZAA, Salma Ketat, Asser I. Ghoneim, Mohamed Katary, Mohammad M. Abd‐Alhaseeb, Fouad A. Zouein, Amgad Albohy, Ahmed Noby Amer, Ahmed F. El‐Yazbi, Ahmed S.F. Belal
Topics & Concepts
ChemistryPropidium iodideApoptosisCell cycle checkpointCell cycleCyclin-dependent kinase 1Cell cultureDrug repositioningNAD+ kinaseReactive oxygen speciesAnnexinBiochemistryCancer researchProgrammed cell deathPharmacologyEnzymeDrugBiologyGeneticsBioactive Compounds and Antitumor AgentsCancer therapeutics and mechanismsGenomics, phytochemicals, and oxidative stress