Inherently chiral calixarenes by a catalytic enantioselective desymmetrizing cross-dehydrogenative coupling
Xin Zhang, Shuo Tong, Jieping Zhu, Mei‐Xiang Wang
Abstract
Reported here is the catalytic enantioselective desymmetrization of calixarene skeletons for the construction of inherently chiral calixarenes through a transannular arene–arene dehydrogenative coupling reaction.
Topics & Concepts
Enantioselective synthesisDesymmetrizationCalixareneFluorenePalladiumChemistryCatalysisIntramolecular forceCombinatorial chemistryLigand (biochemistry)StereochemistryOrganic chemistryMoleculePolymerReceptorBiochemistrySupramolecular Chemistry and ComplexesAxial and Atropisomeric Chirality SynthesisCatalytic Cross-Coupling Reactions