Necrotizing Soft Tissue Infections in South Australia: A 15-Year Review
Patrick Tam, Brendan J. Kennedy, Anushia Ashokan
Abstract
Abstract Necrotizing soft tissue infections (NSTIs) are associated with high morbidity and mortality. We retrospectively examined the impact of empiric antimicrobials coupled with early surgery on mortality in NSTI. Early surgery independently reduced 30-day mortality (odds ratio, .16; 95% confidence interval, .05–.51; P < .001) that was not further augmented by empiric antimicrobial choice.
Topics & Concepts
MedicinePathogenic organismSoft tissuePathologyIntensive care medicineMicrobiologyBiologyStreptococcal Infections and TreatmentsOtolaryngology and Infectious DiseasesAntimicrobial Resistance in Staphylococcus