Cis-regulatory chromatin loops arise before TADs and gene activation, and are independent of cell fate during early Drosophila development
Sergio Espínola, Markus Götz, Maëlle Bellec, Olivier Messina, Jean-Bernard Fiche, Christophe Houbron, Matthieu Dejean, Ingolf Reim, Andrés M. Cardozo Gizzi, Mounia Lagha, Marcelo Nöllmann
Topics & Concepts
Multicellular organismBiologyChromatinEnhancerCell fate determinationTranscription factorPromoterComputational biologyRegulation of gene expressionTranscriptional regulationGeneGeneticsChIA-PETCell biologyNucleosomeGene expressionGenomics and Chromatin DynamicsRNA Research and SplicingChromosomal and Genetic Variations