Homer1a regulates Shank3 expression and underlies behavioral vulnerability to stress in a model of Phelan-McDermid syndrome
Raozhou Lin, Lisa N. Learman, Muhammad Bangash, Tatiana Melnikova, Erica Leyder, Sai C. Reddy, Nirinjini Naidoo, Joo Min Park, Alena Savonenko, Paul F. Worley
Abstract
mice. Studies highlight the interaction between stress and genetics and focus attention on activity-dependent changes that may contribute to pathogenesis.
Topics & Concepts
Vulnerability (computing)BiologyGeneticsNeuroscienceCell biologyComputer scienceComputer securityGenetics and Neurodevelopmental DisordersCongenital heart defects researchAutism Spectrum Disorder Research