A Human In Vitro T Cell Exhaustion Model for Assessing Immuno-Oncology Therapies
Lynne S. Dunsford, Rosie H. Thoirs, Emma Rathbone, Agapitos Patakas
Topics & Concepts
CD28Cytotoxic T cellCancer researchDownregulation and upregulationTumor microenvironmentImmunologyBlockadeT cellIn vitroCytokinePhenotypeMedicineBiologyImmune systemReceptorInternal medicineGeneBiochemistryCancer Immunotherapy and BiomarkersCAR-T cell therapy researchImmune Cell Function and Interaction