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Knoevenagel Condensation and Michael Addition in Bio‐Renewable Deep Eutectic Solvent: Facile Synthesis of a Library of Bis‐enol Derivatives

Suman Srivastava

2020ChemistrySelect23 citationsDOI

Abstract

Abstract Choline chloride and polyethylene glycol based bio‐renewable deep eutectic solvent displayed remarkable activity for the synthesis of bis‐enol scaffolds via knoevenegal condensation followed by michael addition. The green and bio‐renewable deep eutectic solvent is found to be mild, non‐toxic, bio‐compatible, with significant features such as excellent yields, facile preparation, and biodegradable with good recyclability.

Topics & Concepts

Deep eutectic solventCholine chlorideSolventKnoevenagel condensationMichael reactionPolyethylene glycolEutectic systemOrganic chemistryChemistryEnolMaterials scienceCatalysisAlloyIonic liquids properties and applicationsChemical Synthesis and ReactionsOxidative Organic Chemistry Reactions