Pan-retroviral Nucleocapsid-Mediated Phase Separation Regulates Genomic RNA Positioning and Trafficking
Anne Monette, Meijuan Niu, Lois Chen, Shringar Rao, Robert J. Gorelick, Andrew J. Mouland
Abstract
-dependent feature of virus replication represents a critical target for pan-antiretroviral therapies.
Topics & Concepts
Stress granuleRibonucleoproteinCell biologyRNARetrovirusBiologyZinc fingerViral replicationVirologyChemistryVirusMolecular biologyMessenger RNAGeneticsGeneTranslation (biology)Transcription factorRNA Research and SplicingRNA and protein synthesis mechanismsRNA modifications and cancer