MCART1/SLC25A51 is required for mitochondrial NAD transport
Nora Kory, Jelmi uit de Bos, Sanne van der Rijt, Nevena Jankovic, Miriam A. Güra, Nicholas L. Arp, Izabella A. Pena, Gyan Prakash, Sze Ham Chan, Tenzin Kunchok, Caroline A. Lewis, David M. Sabatini
Abstract
transporter, can functionally complement for each other. Thus, we propose that MCART1 is the long sought mitochondrial transporter for NAD in human cells.
Topics & Concepts
NAD+ kinaseMitochondrionChemistryBiochemistryBiologyEnzymeMitochondrial Function and PathologyRNA modifications and cancerAutophagy in Disease and Therapy