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Tryptanthrin suppresses double-stranded RNA-induced CXCL10 expression via inhibiting the phosphorylation of STAT1 in human umbilical vein endothelial cells

Shogo Kawaguchi, Hirotake Sakuraba, Hidezumi Kikuchi, Noriyuki Numao, Taka Asari, Hiroto Hiraga, Jiangli Ding, Tomoh Matsumiya, Kazuhiko Seya, Shinsaku Fukuda, Tadaatsu Imaizumi

2020Molecular Immunology15 citationsDOI

Topics & Concepts

CXCL10Umbilical veinIRF3ChemistryTLR3InterferonChemokineTRIFMolecular biologyCell biologyBiologyInnate immune systemReceptorBiochemistryToll-like receptorIn vitroImmunologyImmune Cell Function and InteractionCancer-related molecular mechanisms researchinterferon and immune responses
Tryptanthrin suppresses double-stranded RNA-induced CXCL10 expression via inhibiting the phosphorylation of STAT1 in human umbilical vein endothelial cells | Litcius