Maternal organic selenium supplementation during gestation improves the antioxidant capacity and reduces the inflammation level in the intestine of offspring through the NF-κB and ERK/Beclin-1 pathways
Daolin Mou, Dajiang Ding, Min Yang, Xuemei Jiang, Lianpeng Zhao, Lianqiang Che, Zhengfeng Fang, Shengyu Xu, Yan Lin, Yong Zhuo, Jian Li, Chao Huang, Yuanfeng Zou, Lixia Li, De Wu, Bin Feng
Abstract
groups. In conclusion, maternal HMSeBA supplementation during gestation can improve the offspring's intestinal antioxidant capacity and reduce the inflammation level by suppressing NF-κB and ERK/Beclin-1 signaling.
Topics & Concepts
OffspringGestationAntioxidantInflammationSeleniumMAPK/ERK pathwayAntioxidant capacityNF-κBPregnancySignal transductionBiologyInternal medicineEndocrinologyChemistryImmunologyMedicineBiochemistryGeneticsOrganic chemistrySelenium in Biological SystemsBirth, Development, and HealthMedical and Biological Ozone Research