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Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist

Alexandra Litvinchuk, Jung H. Suh, Jing Guo, Karin Lin, Sonnet S. Davis, Nga Bien‐Ly, Eric Tycksen, G. Travis Tabor, Javier Remolina Serrano, Melissa Manis, Xin Bao, Choonghee Lee, Megan E. Bosch, Enmanuel J. Perez, Carla M. Yuede, Anil G. Cashikar, Jason D. Ulrich, Gilbert Di Paolo, David M. Holtzman

2023Neuron135 citationsDOIOpen Access PDF

Topics & Concepts

NeurodegenerationAgonistNeuroscienceLiver X receptorChemistryBiologyMedicineReceptorInternal medicineBiochemistryNuclear receptorDiseaseGeneTranscription factorCholesterol and Lipid MetabolismNeuroinflammation and Neurodegeneration MechanismsImmune cells in cancer
Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist | Litcius