Tadalafil alleviates cisplatin-induced reproductive toxicity through the activation of the Nrf2/HO-1 pathway and the inhibition of oxidative stress and apoptosis in male rats
Basel A. Abdel‐Wahab, Saad A. Alkahtani, Ehab A. M. Elagab
Topics & Concepts
Oxidative stressDownregulation and upregulationTadalafilToxicityReproductive toxicityApoptosisPharmacologyAntioxidantcGMP-specific phosphodiesterase type 5BiologyEndocrinologyMedicineInternal medicineErectile dysfunctionBiochemistryGeneChemotherapy-induced organ toxicity mitigationReproductive Biology and FertilityPregnancy and Medication Impact