Litcius/Paper detail

Synthetic lethal strategies for the development of cancer therapeutics

Natalie Y.L. Ngoi, David Gallo, Carlos Torrado, Mirella Nardo, Daniel Durocher, Timothy A. Yap

2024Nature Reviews Clinical Oncology61 citationsDOI

Topics & Concepts

Synthetic lethalityCRISPRMedicineComputational biologyEpigeneticsDrug discoveryBioinformaticsDNA repairBiologyGeneticsDNAGeneCRISPR and Genetic EngineeringPARP inhibition in cancer therapyDNA Repair Mechanisms