Carvedilol prevents pancreatic β-cell damage and the development of type 1 diabetes in mice by the inhibition of proinflammatory cytokines, NF-κB, COX-2, iNOS and oxidative stress
Keyvan Amirshahrokhi, Ali Zohouri
Topics & Concepts
Proinflammatory cytokineCarvedilolEndocrinologyInternal medicineStreptozotocinNitric oxide synthaseOxidative stressInflammationPancreatic isletsNitric oxideTumor necrosis factor alphaMalondialdehydeMedicineDiabetes mellitusChemistryIsletHeart failurePancreatic function and diabetesDiabetes and associated disordersDiabetes Management and Research