Nanotuner targeting mitochondrial redox and iron homeostasis imbalance for the treatment of acute liver injury
Minghao Li, Qiwei Yang, Jie Gao, Xudong Liu, Jihua Shi, Wenzhi Guo, Yi Zhang, Qiwen Yu, Xinzhi Sun, Shuijun Zhang
Abstract
: Our findings establish this dual-targeting nanotuner as a promising therapeutic strategy for ALI, providing novel insights into mitochondrial redox and iron homeostasis modulation.
Topics & Concepts
Iron homeostasisHomeostasisRedoxMitochondrionMedicineChemistryCell biologyBiologyInternal medicineBiochemistryMetabolismOrganic chemistryMitochondrial Function and Pathology