DMSO as a dual carbon synthon in one-pot tandem synthesis of <i>N</i>-alkylated quinazolinones from anthranilamides and acetophenones
Pushpendra Yadav, Sourabh Yadav, Annapurna Awasthi, Mandalparthi Phanindrudu, Suman Bhowmick, Dharmendra Kumar Tiwari
Abstract
DMSO-assisted approach for the synthesis of N -alkylated quinazolinones from readily available 2-aminobenzamide and aryl methyl ketones has been developed. DMSO played a dual role, acting as a solvent as well as a dual carbon synthon, making this process an environmentally benign approach.
Topics & Concepts
SynthonChemistryAlkylationTandemOrganic chemistrySolventDual (grammatical number)Carbon fibersArylCombinatorial chemistryCatalysisArtComposite numberLiteratureAlkylComposite materialMaterials scienceQuinazolinone synthesis and applicationsSynthesis and Biological EvaluationPhenothiazines and Benzothiazines Synthesis and Activities