Serum TSH levels are associated with postoperative recurrence and lymph node metastasis of papillary thyroid carcinoma.
Yingying Xiang, Yiying Xu, Adheesh Bhandari, Namita Sindan, Suzita Hirachan, Qing Yang, Gui-Long Guo, Yanyan Shen
Abstract
OBJECTIVE: To explore the relationship between thyroid-stimulating hormone (TSH) levels in the serum and postoperative recurrence and lymph node metastasis (LNM) in papillary thyroid cancer (PTC) patients after surgery. METHODS: gene mutation before surgery by fine-needle aspiration (FNA) cytology, and TSH levels in the serum were determined one month after surgery. The optimal cut-off value of thyroid-stimulating hormone (TSH) for predicting the recurrence or metastasis of PTC after surgery was determined by the establishment of a receiver operating characteristic (ROC) curve. Kaplan-Meier and Cox regression analyses were used to evaluate the correlation between the optimal cut-off value of TSH and disease-free survival rate and prognosis. RESULTS: ). CONCLUSION: population.