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CARD domains mediate anti-phage defence in bacterial gasdermin systems

Tanita Wein, Adi Millman, Kathrin Lange, Erez Yirmiya, Romi Hadary, Jeremy Garb, Sarah Melamed, Gil Amitai, Orly Dym, Felix Steinruecke, Aidan B. Hill, Philip J. Kranzusch, Rotem Sorek

2025Nature30 citationsDOIOpen Access PDF

Topics & Concepts

Pyrin domainInflammasomeBiologyCell biologyInnate immune systemPhage displayAIM2Bacterial cell structureCaspaseImmune systemProgrammed cell deathComputational biologyBacteriaGeneticsReceptorAntibodyApoptosisInflammasome and immune disordersToxoplasma gondii Research StudiesStreptococcal Infections and Treatments
CARD domains mediate anti-phage defence in bacterial gasdermin systems | Litcius