Trio Role of Deep Eutectic Solvents in the Green Synthesis of 1,4-Dihydropyridine Synthesis <i>via</i> Hantzsch Reaction
Gobind Kumar, Gaurav Bhargava, Rupesh Kumar
Abstract
Here, we have reported a novel deep eutectic solvent (DES) with tremendous activity for the synthesis of dihydropyridines. DESs have played a trio role in the reaction. It acts as a green catalyst, solvent, and in-situ substrate in this chemical reaction. This method offers various advantages such as metal-free catalysis, green solvent, high yields of the products, and short reaction time.
Topics & Concepts
ChemistryDeep eutectic solventCatalysisEutectic systemSolventSubstrate (aquarium)Green chemistryReaction conditionsCombinatorial chemistryOrganic chemistryDihydropyridineMetalReaction mechanismCalciumOceanographyAlloyGeologyMulticomponent Synthesis of HeterocyclesChemistry and Chemical EngineeringMicrowave-Assisted Synthesis and Applications