The m6A reader YTHDC2 promotes SIRT3 expression by reducing the stabilization of KDM5B to improve mitochondrial metabolic reprogramming in diabetic peripheral neuropathy
Yang Jiao, Shu Wang, Xin Wang, Ling Yin, Yue-Hua Zhang, Yize Li, Yonghao Yu
Topics & Concepts
Downregulation and upregulationCell biologyMitochondrionMessenger RNANeurodegenerationBiologyPeripheral neuropathyDiabetes mellitusChemistryBiochemistryEndocrinologyInternal medicineGeneMedicineDiseaseSirtuins and Resveratrol in MedicineRNA modifications and cancerProtein Degradation and Inhibitors