Impact of the gonococcal FC428 <i>penA</i> allele 60.001 on ceftriaxone resistance and biological fitness
Ke Zhou, Shao-Chun Chen, Fan Yang, Stijn van der Veen, Yue-Ping Yin
Abstract
allele 60.001 is essential for ceftriaxone resistance of the FC428 clone, while its impact on biological fitness is dependent on the specific growth conditions.
Topics & Concepts
CeftriaxoneBiologyAlleleMutantMicrobiologyNeisseria gonorrhoeaeGeneticsAntibioticsGeneReproductive tract infections researchBacterial Infections and VaccinesSyphilis Diagnosis and Treatment