Future directions for medicinal chemistry in the field of oligonucleotide therapeutics
Jonathan Hall
Abstract
In the last decade, the field of oligonucleotide therapeutics has matured, with the regulatory approval of several single-stranded and double-stranded RNA drugs. In this Perspective, I discuss enabling developments and likely future directions in the field from the perspective of oligonucleotide chemistry.
Topics & Concepts
OligonucleotideBiologyComputational biologyPerspective (graphical)Field (mathematics)RNAComputer scienceBiochemistryDNAMathematicsGeneArtificial intelligencePure mathematicsRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniquesDNA and Nucleic Acid Chemistry